2-[4-(chloromethyl)phenyl]propanoic acid
2-(4-Chloromethylphenyl)propionic acid
CAS: 80530-55-8
Molecular Formula: C10H11ClO2
2-[4-(chloromethyl)phenyl]propanoic acid - Names and Identifiers
| Name | 2-(4-Chloromethylphenyl)propionic acid |
| Synonyms | CMPPA 2-(4-cloromethyl)phenylpropionic acid 2-(4-Chloromethylphenyl)propionic acid 2-[4-(chloromethyl)phenyl]propanoicaci 2-(4-Chloromethylphenyl) propionic acid 2-[4-(chloromethyl)phenyl]propanoic acid Benzeneacetic acid, 4-(chloromethyl)-α-methyl- 4-(Chloromethyl)-alpha-methylbenzeneacetic acid |
| CAS | 80530-55-8 |
| InChI | InChI=1/C10H11ClO2/c1-7(10(12)13)9-4-2-8(6-11)3-5-9/h2-5,7H,6H2,1H3,(H,12,13) |
2-[4-(chloromethyl)phenyl]propanoic acid - Physico-chemical Properties
| Molecular Formula | C10H11ClO2 |
| Molar Mass | 198.65 |
| Density | 1.227 |
| Boling Point | 333 °C |
| Flash Point | 155 °C |
| Vapor Presure | 5.44E-05mmHg at 25°C |
| Refractive Index | 1.552 |
2-[4-(chloromethyl)phenyl]propanoic acid - Introduction
2-(4-Chlorometylphenyl) propionic acid is an organic compound with the chemical formula C10H11ClO2. The following is an introduction to its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-melting point: 58-60 ℃
-Boiling point: 350 ℃ (decomposition)
-Solubility: Soluble in alcohol and ether, slightly soluble in water.
Use:
- 2-(4-Chloromethylphenyl)propionic acid is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. It is widely used to relieve pain and discomfort caused by inflammation, such as arthritis, rheumatoid arthritis, etc.
Preparation Method:
The preparation method of 2-(4-Chloromethylphenyl)propionic acid is as follows:
1. p-Toluene is reacted with mixed acid (sulfuric acid and nitric acid) to obtain p-methylphenylformic acid.
2. p-methylphenylformic acid reacts with chloromethanol to generate 2-(4-Chloromethylphenyl)propionic acid through esterification.
Safety Information:
- 2-(4-Chloromethylphenyl)propionic acid is irritating and should be avoided in contact with skin, eyes and mucous membranes.
-Wear appropriate personal protective equipment such as gloves and goggles when using.
-Avoid inhaling dust and operate in a well-ventilated place.
-Keep away from ignition and oxidizing agents during use or storage.
-If inhaling or eating by accident, seek medical help and bring the packaging or label to the hospital.
Please note that this information is for reference only. Please carefully read and comply with the product's chemical safety instructions and relevant regulations.
Nature:
-Appearance: White crystal or crystalline powder
-melting point: 58-60 ℃
-Boiling point: 350 ℃ (decomposition)
-Solubility: Soluble in alcohol and ether, slightly soluble in water.
Use:
- 2-(4-Chloromethylphenyl)propionic acid is a non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic effects. It is widely used to relieve pain and discomfort caused by inflammation, such as arthritis, rheumatoid arthritis, etc.
Preparation Method:
The preparation method of 2-(4-Chloromethylphenyl)propionic acid is as follows:
1. p-Toluene is reacted with mixed acid (sulfuric acid and nitric acid) to obtain p-methylphenylformic acid.
2. p-methylphenylformic acid reacts with chloromethanol to generate 2-(4-Chloromethylphenyl)propionic acid through esterification.
Safety Information:
- 2-(4-Chloromethylphenyl)propionic acid is irritating and should be avoided in contact with skin, eyes and mucous membranes.
-Wear appropriate personal protective equipment such as gloves and goggles when using.
-Avoid inhaling dust and operate in a well-ventilated place.
-Keep away from ignition and oxidizing agents during use or storage.
-If inhaling or eating by accident, seek medical help and bring the packaging or label to the hospital.
Please note that this information is for reference only. Please carefully read and comply with the product's chemical safety instructions and relevant regulations.
Last Update：2024-04-09 15:18:00
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